Antimicrobial Impact of Different Air-Polishing Powders in a Subgingival Biofilm Model

• Main Authors: Johannes-Simon Wenzler (Author), Felix Krause (Author), Sarah Böcher (Author), Wolfgang Falk (Author), Axel Birkenmaier (Author), Georg Conrads (Author), Andreas Braun (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Subgingival air-polishing devices (SAPD) can reduce bacterial biofilms and thus support periodontal healing. The authors of this study evaluated the effectiveness of the glycine-based and trehalose-based air-polishing powders in removing pathogenic bacteria in a subgingival biofilm model. We treated 56 subgingival pockets in porcine jaws with SAPD. Subgingival air polishing was performed in three groups of 13 pockets each: I, glycine-based powder; II, trehalose-based powder; and III, water alone. Another group (IV) served as untreated controls. Prior to air polishing, inoculated titanium bars were inserted into the pockets containing periopathogenic bacteria such as <i>Porphyromonas gingivalis</i> and <i>Tannerella forsythia</i>. Remaining bacteria were evaluated using real-time PCR. The numbers of remaining bacteria depended on the treatment procedure, with the lowest number of total bacteria in group I (median: 1.96 × 10⁶ CFU; min: 1.46 × 10⁵; max: 9.30 × 10⁶). Both polishing powders in groups I and II (median: 1.36 × 10⁷ CFU; min: 5.22 × 10⁵; max: 7.50 × 10⁷) showed a statistically significantly lower total bacterial load in comparison to both group IV (median: 2.02 × 10⁸ CFU; min: 5.14 × 10⁷; max: 4.51 × 10⁸; <i>p</i> < 0.05) and group III (median: 4.58 × 10⁷ CFU; min: 2.00 × 10⁶; max: 3.06 × 10⁸; <i>p</i> < 0.05). Both subgingival air-polishing powders investigated can reduce periopathogenic bacteria and thus support antimicrobial therapy approaches in periodontal treatment regimens.

Item Description

10.3390/antibiotics10121464
2079-6382