Update on Pediatric Sepsis in Mexico

The main objective of this work was to determine and update the causal agents' antibiotic sensitivity and resistance patterns on pediatric sepsis in a population of northeast Mexico. It is a cross-sectional study showing the results of blood cultures of pediatric patients with a presumptive dia...

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Main Authors: Crisell Arely Donath Benitez (Author), Estefanía Mattenberger-Cantú (Author), Ricardo Salas-Flores (Author), Guillermo Baudelio Gómez-Morales (Author), Paola Alejandra Mártinez-Diaz (Author), María Guadalupe Moreno-Treviño (Author), Laura Elvira García-Tovar (Author), Francisco González-Salazar (Author)
Format: Book
Published: SAGE Publishing, 2022-08-01T00:00:00Z.
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Summary:The main objective of this work was to determine and update the causal agents' antibiotic sensitivity and resistance patterns on pediatric sepsis in a population of northeast Mexico. It is a cross-sectional study showing the results of blood cultures of pediatric patients with a presumptive diagnosis of sepsis were reviewed according to the SOFA criteria during 2020 in a public hospital in Mexico. A total of 207 blood cultures were performed and analyzed. The main isolated microorganisms were Staphylococcus, followed by Klebsiella and Escherichia. Several microorganisms showed 100% of sensitivity to different antibiotics or antifungals, some of them include Vancomycin, Voriconazole, Meropenem, Ciprofloxacin, and Cefotaxime. Bacteria of genre Staphylococcus showed its highest sensitivity rate to Tigecycline with 63.3%. Too Staphylococcus showed the highest resistance rate to Oxacillin with 50%. Although the patterns of sepsis-causing germs are similar to those previously reported, the development of new drugs with greater efficacy is the main contribution.
Item Description:2333-794X
10.1177/2333794X221118017