Evaluation of the pharmacokinetics of trazpiroben (TAK‐906) in the presence and absence of the proton pump inhibitor esomeprazole
Abstract Trazpiroben, a dopamine D2/D3 receptor antagonist under development to treat gastroparesis, displays decreasing solubility with increasing pH. This single‐sequence, open‐label, two‐period, crossover study evaluated the effect of esomeprazole, a proton pump inhibitor that raises gastric pH,...
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Main Authors: | Jatinder Kaur Mukker (Author), George Dukes (Author), Lisi Wang (Author), Susanna Huh (Author), Polyna Khudyakov (Author), Mitsuhiro Nishihara (Author), Chunlin Chen (Author) |
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Format: | Book |
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Wiley,
2022-05-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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