Phenotype-Driven Virtual Panel Is an Effective Method to Analyze WES Data of Neurological Disease

• Prif Awduron: Xu Wang (Awdur), Xiang Shen (Awdur), Fang Fang (Awdur), Chang-Hong Ding (Awdur), Hao Zhang (Awdur), Zhen-Hua Cao (Awdur), Dong-Yan An (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Objective: Whole Exome Sequencing (WES) is an effective diagnostic method for complicated and multi-system involved rare diseases. However, annotation and analysis of the WES result, especially for single case analysis still remain a challenge. Here, we introduce a method called phenotype-driven des...