Phenotype-Driven Virtual Panel Is an Effective Method to Analyze WES Data of Neurological Disease

• Автори: Xu Wang (Автор), Xiang Shen (Автор), Fang Fang (Автор), Chang-Hong Ding (Автор), Hao Zhang (Автор), Zhen-Hua Cao (Автор), Dong-Yan An (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Objective: Whole Exome Sequencing (WES) is an effective diagnostic method for complicated and multi-system involved rare diseases. However, annotation and analysis of the WES result, especially for single case analysis still remain a challenge. Here, we introduce a method called phenotype-driven des...