A family with Milroy disease caused by the FLT4/VEGFR3 gene variant c.2774 T > A

• Main Authors: Yu Sui (Author), Yongping Lu (Author), Meina Lin (Author), Xiang Ni (Author), Xinren Chen (Author), Huan Li (Author), Miao Jiang (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Milroy disease (MD) is a rare, autosomal-dominant disorder. Variants in the Fms-related tyrosine kinase 4 (FLT4/VEGFR3) gene cause the symptoms of this disease. In this report, we investigated the variant in a large Chinese family with MD. Methods We conducted Sanger sequencing o...