Experimental Evaluation of Anticancer Efficiency and Acute Toxicity of Anthrafuran for Oral Administration

• Main Authors: Andrey E. Shchekotikhin (Author), Helen M. Treshalina (Author), Michael I. Treshchalin (Author), Eleonora R. Pereverzeva (Author), Helen B. Isakova (Author), Alexander S. Tikhomirov (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The new antitumor agent anthrafuran has demonstrated a consistent effect in murine tumor models when administered parenterally due to the simultaneous inhibition of multiple cellular targets such as topoisomerases I/II and protein kinases. In this study, we assessed the anticancer efficiency and acu...