Cost-effectiveness of obinutuzumab plus bendamustine in Chinese patients with relapse and refractory follicular lymphoma

A decision analytic model was constructed to assess the cost-effectiveness of obinutuzumab plus bendamustine followed by obinutuzumabmaintenance therapy (O-B-O) in Chinese patients with relapsed and refractory follicular lymphoma (rrFL). O-B-O was associated with a dominant or more favorable cost-ef...

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Bibliographic Details
Main Authors: Jun Ma (Author), Donglu Zhao (Author), Bihong Zhen (Author), Yan Xia (Author), Qianyi Gong (Author), Wendong Chen (Author)
Format: Book
Published: Becaris Publishing Limited, 2023-11-01T00:00:00Z.
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Summary:A decision analytic model was constructed to assess the cost-effectiveness of obinutuzumab plus bendamustine followed by obinutuzumabmaintenance therapy (O-B-O) in Chinese patients with relapsed and refractory follicular lymphoma (rrFL). O-B-O was associated with a dominant or more favorable cost-effectiveness than the conventional therapies. Survival outcomes, quality of life of progression free survival, and subsequent treatment costs for progressive disease were the main drivers of the cost- effectiveness of O-B-O. The cost-effectiveness proportions of O-B-O relative to conventional therapies under the recommended cost-effectiveness threshold ranged from 61.0% to 99.9%. Thus, O-B-O was highly cost-effective for treating patients with rrFL in China compared with conventional therapies.
Item Description:10.57264/cer-2023-0073
2042-6313