iNKT Cell Activation Exacerbates the Development of Huntington's Disease in R6/2 Transgenic Mice

• المؤلفون الرئيسيون: Hyun Jung Park (مؤلف), Sung Won Lee (مؤلف), Wooseok Im (مؤلف), Manho Kim (مؤلف), Luc Van Kaer (مؤلف), Seokmann Hong (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2019-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Huntington's disease (HD) is an inherited neurodegenerative disorder which is caused by a mutation of the huntingtin (HTT) gene. Although the pathogenesis of HD has been associated with inflammatory responses, if and how the immune system contributes to the onset of HD is largely unknown. Invar...