iNKT Cell Activation Exacerbates the Development of Huntington's Disease in R6/2 Transgenic Mice

• Hauptverfasser: Hyun Jung Park (Verfasst von), Sung Won Lee (Verfasst von), Wooseok Im (Verfasst von), Manho Kim (Verfasst von), Luc Van Kaer (Verfasst von), Seokmann Hong (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2019-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Huntington's disease (HD) is an inherited neurodegenerative disorder which is caused by a mutation of the huntingtin (HTT) gene. Although the pathogenesis of HD has been associated with inflammatory responses, if and how the immune system contributes to the onset of HD is largely unknown. Invar...