iNKT Cell Activation Exacerbates the Development of Huntington's Disease in R6/2 Transgenic Mice

• Главные авторы: Hyun Jung Park (Автор), Sung Won Lee (Автор), Wooseok Im (Автор), Manho Kim (Автор), Luc Van Kaer (Автор), Seokmann Hong (Автор)
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• Опубликовано: Hindawi Limited, 2019-01-01T00:00:00Z.
• Предметы: article
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Huntington's disease (HD) is an inherited neurodegenerative disorder which is caused by a mutation of the huntingtin (HTT) gene. Although the pathogenesis of HD has been associated with inflammatory responses, if and how the immune system contributes to the onset of HD is largely unknown. Invar...