Host alternation is necessary to maintain the genome stability of rift valley fever virus.

• Main Authors: Sara Moutailler (Author), Benjamin Roche (Author), Jean-Michel Thiberge (Author), Valérie Caro (Author), François Rougeon (Author), Anna-Bella Failloux (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Most arthropod-borne viruses (arboviruses) are RNA viruses, which are maintained in nature by replication cycles that alternate between arthropod and vertebrate hosts. Arboviruses appear to experience lower rates of evolution than RNA viruses that replicate in a single host. This genetic...