Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway

• Главные авторы: Wei Zhao (Автор), Shasha Feng (Автор), Jian Wang (Автор), Zhenshuai Zhang (Автор), Lu Chen (Автор), Li Jiang (Автор), Ming Li (Автор), Tianxiao Wang (Автор)
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• Опубликовано: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Предметы: article
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Cancer targeted therapy is essential to minimize damage to normal cells and improve treatment outcomes. The elevated activity of Cystathionine beta-synthase (CBS), an enzyme responsible for producing endogenous hydrogen sulfide (H2S), plays a significant role in promoting tumor growth, invasiveness,...