The 46.1 Antibody Mediates Neurotensin Uptake into the CNS and the Effects Depend on the Route of Intravenous Administration
Central nervous system (CNS) exposure to blood-borne biotherapeutics is limited by the restrictive nature of the brain vasculature. In particular, tightly sealed endothelial cells of the blood-brain barrier (BBB) prevent the uptake of protein and gene medicines. An approach to increase the bioavaila...
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Main Authors: | Julia V. Georgieva (Author), Moriah Katt (Author), Zhou Ye (Author), Benjamin J. Umlauf (Author), Cody J. Wenthur (Author), Eric V. Shusta (Author) |
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Format: | Book |
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MDPI AG,
2022-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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