Cover Image

Cutaneous Components Leading to Pruritus, Pain, and Neurosensitivity in Atopic Dermatitis: A Narrative Review

Abstract Atopic dermatitis (AD) is a chronic, relapsing immunoinflammatory skin condition characterized by sensations such as pruritis, pain, and neuronal hypersensitivity. The mechanisms underlying these sensations are multifactorial and involve complex crosstalk among several cutaneous components....

Full description

Saved in:

Bibliographic Details
Main Authors:	Sonja Ständer (Author), Thomas Luger (Author), Brian Kim (Author), Ethan Lerner (Author), Martin Metz (Author), Roni Adiri (Author), Juliana M. Canosa (Author), Amy Cha (Author), Gil Yosipovitch (Author)
Format:	Book
Published:	Adis, Springer Healthcare, 2024-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Emerging Methods to Objectively Assess Pruritus in Atopic Dermatitis
by: Mary Patricia Smith, et al.
Published: (2019)

Early Relief of Pruritus in Atopic Dermatitis with Crisaborole Ointment, A Non-steroidal, Phosphodiesterase 4 Inhibitor
by: Gil Yosipovitch, et al.
Published: (2018)

Validation of the Itch Severity Item as a Measurement Tool for Pruritus in Patients with Psoriasis: Results from a Phase 3 Tofacitinib Program
by: Sonja Ständer, et al.
Published: (2017)

Pruritus and Atopic Dermatitis: from Etiological Features to Management
by: Nikolay N. Murashkin, et al.
Published: (2020)

Characteristics of Pruritus in Relation to Self-assessed Severity of Atopic Dermatitis
by: Flavien Huet, et al.
Published: (2018)

The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus
by: Pawinee Rerknimitr, et al.
Published: (2017)

Direct and Indirect Effects of Crisaborole Ointment on Quality of Life in Patients with Atopic Dermatitis: A Mediation Analysis
by: Eric L. Simpson, et al.
Published: (2019)

Transcutaneous Slowly Depolarizing Currents Elicit Pruritus in Patients with Atopic Dermatitis
by: Roman Rukwied, et al.
Published: (2020)

Itch improvement has a major and comparable effect on the Dermatology Life Quality Index in psoriasis and atopic dermatitis patients
by: Wolf‐Henning Boehncke, et al.
Published: (2024)

Criteria Suggestive of Psychological Components of Itch and Somatoform Itch: Study of a Large Sample of Patients with Chronic Pruritus
by: Gudrun Schneider, et al.
Published: (2020)

Chronic pruritus in atopic dermatitis - mechanisms and different ways of treatment, affect on quality of life
by: Sandra Ostaszewska, et al.
Published: (2023)

The Anti-Inflammatory and Anti-Pruritus Mechanisms of Huanglian Jiedu Decoction in the Treatment of Atopic Dermatitis
by: Yubin Xu, et al.
Published: (2021)

Clinical aspect of pruritus in pediatric atopic dermatitis: A study from Western India
by: Yogesh Shah, et al.
Published: (2023)

Two Cancer Patients Receiving Dupilumab for Treatment of Atopic Dermatitis
by: Emilie Fowler, et al.
Published: (2019)

Stable Response and Sustained Improvement of Itch and Sleep Symptoms in Patients with Atopic Dermatitis Treated with Lebrikizumab over 52 Weeks
by: Gil Yosipovitch, et al.
Published: (2024)

Pruritus in Keloid Scars: Mechanisms and Treatments
by: Ahmed A. Hawash, et al.
Published: (2021)

Managing Atopic Dermatitis with Lebrikizumab – The Evidence to Date
by: Labib A, et al.
Published: (2022)

Current Clinical Options for the Management of Itch in Atopic Dermatitis
by: Lipman ZM, et al.
Published: (2021)

Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions
by: Gil Yosipovitch, et al.
Published: (2019)

The Role of a Novel Generation of Emollients, ‘Emollients Plus’, in Atopic Dermatitis
by: Araviiskaia E, et al.
Published: (2022)

Successful Treatment of Epidermal Nevus-associated Pruritus with Topical Ketamine-Amitriptyline-Lidocaine
by: Jose A. Jaller, et al.
Published: (2017)

A Qualitative Tool to Guide in the Interpretation of the Numerical Rating Scale for Pruritus Intensity in Patients with Atopic Dermatitis
by: Ignasi Figueras, et al.
Published: (2024)

Chronic Pruritus of Unknown Origin: Clinical Profile and Disease-Related Burden
by: Manuel P. Pereira, et al.
Published: (2021)

Patients with Moderate-to-Severe Atopic Dermatitis Maintain Stable Response with No or Minimal Fluctuations with 1 Year of Lebrikizumab Treatment
by: Jonathan I. Silverberg, et al.
Published: (2024)

Release of cervical muscular tension improved severe pruritus in moderate-to-severe atopic dermatitis: A case series
by: Shusaku Hosono, MD, et al.
Published: (2020)

Pruritus in pediatric patients with atopic dermatitis: a multidisciplinary approach - summary document from an Italian expert group
by: May El Hachem, et al.
Published: (2020)

Challenges in Clinical Research and Care in Pruritus
by: Manuel P. Pereira, et al.
Published: (2020)

Genital pruritus is associated with longer hospital stays, higher costs and increased odds of psychiatric hospitalization among inpatient adults with pruritus in the United States-National inpatient sample (2012-2015)
by: Siri Choragudi, et al.
Published: (2024)

A Negative Association of Hypothalamic Volume and Perceived Stress in Patients with Atopic Dermatitis
by: Hideki Mochizuki, et al.
Published: (2020)

Validation of a Comprehensive Set of Pruritus Assessment Instruments: The Chronic Pruritus Tools Questionnaire PRURITOOLS
by: Emely Verweyen, et al.
Published: (2019)

Publisher Correction: Patients with Moderate-to-Severe Atopic Dermatitis Maintain Stable Response with No or Minimal Fluctuations with 1 Year of Lebrikizumab Treatment
by: Jonathan I. Silverberg, et al.
Published: (2024)

Capturing patient-reported sleep disturbance in atopic dermatitis clinical trials
by: Carla Dias-Barbosa, et al.
Published: (2024)

Characteristics of Atopic Dermatitis Patients Treated with Crisaborole: Real-World Data from a Large Healthcare Provider Database in Israel
by: Weil C, et al.
Published: (2022)

Usability of Validated Sleep-assessment Questionnaires in Patients with Chronic Pruritus: An Interview-based Study
by: Theresa Suilmann, et al.
Published: (2018)

DYNAMICS OF ACTIVITY OF SOME COMPONENTS OF COMPLEMENT IN TREATMENT OF ATOPIC DERMATITIS IN CHILDREN
by: S. S. Andina, et al.
Published: (2015)

Patients' and caregivers' perspectives of the atopic dermatitis journey
by: Steven R. Feldman, et al.
Published: (2024)

Cost-effectiveness and Quality of Specialized and Routine Care in a German Cohort of Patients with Chronic Pruritus
by: Svenja Müller, et al.
Published: (2023)

Maintenance of Investigator's Static Global Assessment Response with Once-Daily Crisaborole in Participants with Mild to Moderate Atopic Dermatitis
by: Lawrence F. Eichenfield, et al.
Published: (2024)

Minimal Clinically Important Difference in Chronic Pruritus Appears to be Dependent on Baseline Itch Severity
by: Claudia Riepe, et al.
Published: (2019)

Neuroimmune Mediators of Pruritus in Hispanic Scalp Psoriatic Itch
by: Leigh A. Nattkemper, et al.
Published: (2023)