Preparation of psoralen polymer-lipid hybrid nanoparticles and their reversal of multidrug resistance in MCF-7/ADR cells

• Main Authors: Qingqing Huang (Author), Tiange Cai (Author), Qianwen Li (Author), Yinghong Huang (Author), Qian Liu (Author), Bingyue Wang (Author), Xi Xia (Author), Qi Wang (Author), John C. C. Whitney (Author), Susan P. C. Cole (Author), Yu Cai (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance (MDR) is the leading cause of failure for breast cancer in the clinic. Thus far, polymer-lipid hybrid nanoparticles (PLN) loaded chemotherapeutic agents has been used to overcome MDR in breast cancer. In this study, we prepared psoralen polymer-lipid hybrid nanoparticles (PSO-PL...