Trans-spliced heat shock protein 90 modulates encystation in Giardia lamblia.

• Autori principali: Rishi Kumar Nageshan (Autore), Nainita Roy (Autore), Shatakshi Ranade (Autore), Utpal Tatu (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2014-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

BACKGROUND: Hsp90 from Giardia lamblia is expressed by splicing of two independently transcribed RNA molecules, coded by genes named HspN and HspC located 777 kb apart. The reasons underlying such unique trans-splicing based generation of GlHsp90 remain unclear. PRINCIPLE FINDING: In this study usin...