Cover Image

Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection

The bacterial ATP-competitive GyrB/ParE subunits of type II topoisomerase are important anti-bacterial targets to treat super drug-resistant bacterial infections. Herein we discovered novel pyrrolamide-type GyrB/ParE inhibitors based on the structural modifications of the candidate AZD5099 that was...

Full description

Saved in:
Bibliographic Details
Main Authors: Xintong Zhao (Author), Jing Feng (Author), Jie Zhang (Author), Zunsheng Han (Author), Yuhua Hu (Author), Hui-Hui Shao (Author), Tianlei Li (Author), Jie Xia (Author), Kangfan Lei (Author), Weiping Wang (Author), Fangfang Lai (Author), Yuan Lin (Author), Bo Liu (Author), Kun Zhang (Author), Chi Zhang (Author), Qingyun Yang (Author), Xinyu Luo (Author), Hanyilan Zhang (Author), Chuang Li (Author), Wenxuan Zhang (Author), Song Wu (Author)
Format: Book
Published: Elsevier, 2023-12-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items