Analysis of multiple gene co-expression networks to discover interactions favoring CFTR biogenesis and ΔF508-CFTR rescue
Abstract Background We previously reported that expression of a miR-138 mimic or knockdown of SIN3A in primary cultures of cystic fibrosis (CF) airway epithelia increased ΔF508-CFTR mRNA and protein levels, and partially restored CFTR-dependent chloride transport. Global mRNA transcript profiling in...
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Main Authors: | Matthew D. Strub (Author), Long Gao (Author), Kai Tan (Author), Paul B. McCray (Author) |
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Format: | Book |
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BMC,
2021-10-01T00:00:00Z.
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