Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers.
The anthelmintic praziquantel (±PZQ) serves as a highly effective antischistosomal therapy. ±PZQ causes a rapid paralysis of adult schistosome worms and deleterious effects on the worm tegument. In addition to these activities against the parasite, ±PZQ also modulates host vascular tone in blood ves...
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Main Authors: | Gihan S Gunaratne (Author), Nawal A Yahya (Author), Peter I Dosa (Author), Jonathan S Marchant (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2018-04-01T00:00:00Z.
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