Langerhans cell histiocytosis: A case report of a three year old boy with primary oral manifestations
Langerhans cell histiocytosis (LCH) is a rare disease with formation of granulomatous infiltrations consisting of Langerhans cells, histiocytes, lymphocytes and eosinophilic granulocytes. The ethiopathogenesis of the disease has not been fully clarified yet. It can occur as focal or disseminated for...
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| Main Authors: | , , , |
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| Format: | Book |
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Tehran University of Medical Sciences,
2006-06-01T00:00:00Z.
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| Summary: | Langerhans cell histiocytosis (LCH) is a rare disease with formation of granulomatous infiltrations consisting of Langerhans cells, histiocytes, lymphocytes and eosinophilic granulocytes. The ethiopathogenesis of the disease has not been fully clarified yet. It can occur as focal or disseminated form - acute or chronic. Oral manifestations may be the first signs. This article reports a case of a 3 year old boy with LCH suffering from severe dental mobility and foul breathe. Radiographically, the lesions appeared as well-defined radiolucent defects in maxilla and mandible. The microscopic findings consisted of sheet like arrangements of histiocytes with a mixture of eosinophils and other inflammatory cells. Biochemical tests were within normal limits. |
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| Item Description: | 1024-641X 2008-2444 |