A novel, green and affordable semi-quantitative limit test for 2-aminobutanol impurity in ethambutol hydrochloride bulk and tablets

• Main Authors: Thana Thanayutsiri (Author), Prasopchai Patrojanasophon (Author), Praneet Opanasopit (Author), Tanasait Ngawhirunpat (Author), Theerasak Rojanarata (Author)
• Format: Book
• Published: Pensoft Publishers, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pharmacopoeial limit test for the impurity 2-aminobutanol (AB) in ethambutol hydrochloride (ETB) relies on florescence measurement using a fluorometer. However, this instrument is often unavailable in many laboratories due to its cost. A novel colorimetric method was therefore developed using ge...