Quality by Design Optimization of Cold Sonochemical Synthesis of Zidovudine-Lamivudine Nanosuspensions
Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used to manage HIV/AIDS infection. The compounds require frequent dosing, exhibit unpredictable bioavailability and a side effect profile that includes hepato- and haema-toxicity. A novel pseudo one-solvent bottom-up approach and Design of E...
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Main Authors: | Bwalya A. Witika (Author), Vincent J. Smith (Author), Roderick B. Walker (Author) |
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Format: | Book |
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MDPI AG,
2020-04-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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