Neuropsychotoxicity of Abused Drugs: Potential of Dextromethorphan and Novel Neuroprotective Analogs of Dextromethorphan With Improved Safety Profiles in Terms of Abuse and Neuroprotective Effects
Drug abuse involving dextromethorphan, an antitussive, has been a social problem in various geographic locations since the 1960s. Ironically, high doses of the drug confer neuroprotective activity with central nervous system and behavioral effects. Accumulating evidence suggests that metabolism to p...
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Main Authors: | Eun-Joo Shin (Author), Phil Ho Lee (Author), Hyun Ji Kim (Author), Toshitaka Nabeshima (Author), Hyoung-Chun Kim (Author) |
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Format: | Book |
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Elsevier,
2008-01-01T00:00:00Z.
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