Berberine prevents primary peritoneal adhesion and adhesion reformation by directly inhibiting TIMP-1

• Main Authors: Xin Liu (Author), Yunwei Wei (Author), Xue Bai (Author), Mingqi Li (Author), Huimin Li (Author), Lei Wang (Author), Shuqian Zhang (Author), Xia Li (Author), Tong Zhao (Author), Yang Liu (Author), Rui Geng (Author), Hao Cui (Author), Hui Chen (Author), Ranchen Xu (Author), Heng Liu (Author), Yong Zhang (Author), Baofeng Yang (Author)
• Format: Book
• Published: Elsevier, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peritoneal adhesions are fibrous tissues that tether organs to one another or to the peritoneal wall and represent the major cause of postsurgical morbidity. Enterolysis at repeat surgeries induces adhesion reformation that is more difficult to prevent than primary adhesion. Here we studied the prev...