Transcriptomic and ChIP-sequence interrogation of EGFR signaling in HER2+ breast cancer cells reveals a dynamic chromatin landscape and S100 genes as targets
Abstract Background The Human Epidermal Growth Factor Receptor (EGFR/HER1) can be activated by several ligands including Transforming Growth Factor alpha (TGF-α) and Epidermal Growth Factor (EGF). Following ligand binding, EGFR heterodimerizes with other HER family members, such as HER2 (human epide...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
BMC,
2019-02-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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