Açaí (Euterpe oleracea Mart) seed extract protects against maternal vascular dysfunction, hypertension, and fetal growth restriction in experimental preeclampsia

• मुख्य लेखकों: Alexandre de Souza da Silva (लेखक), Douglas Val Quintans Nunes (लेखक), Lenize Costa dos Reis Marins de Carvalho (लेखक), Izabelle Barcellos Santos (लेखक), Matheus Pontes de Menezes (लेखक), Graziele Freitas de Bem (लेखक), Cristiane Aguiar da Costa (लेखक), Roberto Soares de Moura (लेखक), Angela Castro Resende (लेखक), Dayane Teixeira Ognibene (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2020-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

सारांश

Objective To investigate whether Euterpe oleracea Mart. (açaí) seed extract (ASE) prevents maternal cardiovascular changes and intrauterine growth restriction (IUGR) in experimental preeclampsia (PE). Methods ASE administration (200 mg/kg/day) during mid to late pregnancy in a rat model of L-NAME-induced PE. Results ASE impaired the maternal hypertension and microalbuminuria as well as the lower fetal and placental weight in experimental PE. ASE also prevented the maternal vascular dysfunction and lipoperoxidation in this model. Conclusion ASE protected against maternal cardiovascular changes and IUGR in the L-NAME-induced PE. The protective effect of ASE may be partly explained by its antioxidant property.

वस्तु वर्णन

1064-1955
1525-6065
10.1080/10641955.2020.1754850