Lipotoxic Impairment of Mitochondrial Function in β-Cells: A Review
Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated receptor (PPAR) signaling, enhanced oxidative str...
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Main Authors: | Axel Römer (Author), Thomas Linn (Author), Sebastian F. Petry (Author) |
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Format: | Book |
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MDPI AG,
2021-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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