Bullous systemic lupus erythematosus: An uncommon diagnosis in an 8-year-old girl
Bullous systemic lupus erythematosus (BSLE) is a rare manifestation of SLE, characterized clinically by tense bullae involving photo-exposed areas and histologically by subepidermal bullae with predominantly neutrophilic infiltrate and immunoglobulin (IgG, IgA, and IgM) and C3 deposition at the derm...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Wolters Kluwer Medknow Publications,
2016-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Bullous systemic lupus erythematosus (BSLE) is a rare manifestation of SLE, characterized clinically by tense bullae involving photo-exposed areas and histologically by subepidermal bullae with predominantly neutrophilic infiltrate and immunoglobulin (IgG, IgA, and IgM) and C3 deposition at the dermo-epidermal junction indirect immunoflurosence. Specific diagnostic criteria for this subtype have been developed. However, the presentation in children is relatively uncommon. We report an 8-year-old girl diagnosed by histopathology and immunological examination as a case of BSLE without any clinical feature of SLE except photosensitivity. This highlights the importance of considering BSLE as a differential diagnosis in case of children presenting with tense bullae. |
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| Item Description: | 2319-7250 10.4103/2319-7250.172468 |