Coexistence of Allergic Diseases in Pediatric Systemic Lupus Erythematosus Patients: Prevalence, Clinical manifestation and Severity

• Main Authors: Porntipa Suebsarakam MD (Author), Kitiporn kaweeyanont MD (Author), Sureeporn Srisutthikamol APN (Author), Dara Mairiang MD (Author)
• Format: Book
• Published: SAGE Publishing, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2333-794X; 10.1177/2333794X241251615
• Keywords: Pediatrics; RJ1-570
• Source: Global Pediatric Health, Vol 11 (2024)

Objective . This study aimed to evaluate allergic diseases in pediatric patients with SLE and their association with SLE disease activity. Method . Patients with SLE aged ≤18 years were enrolled. Allergic diseases were screened using the International Study of Asthma and Allergies in Childhood questionnaire. Patients with a positive allergic disease screen were evaluated by a pediatric allergist for diagnostic confirmation and severity assessment. Results . Out of 118 patients, 16 patients (13.56%) were confirmed to have 1 or more allergic diseases; fourteen with allergic rhinitis, 4 with asthma, and 2 with atopic dermatitis. Two patients had severe-persistent allergic rhinitis and one patient had undiagnosed, uncontrolled severe asthma. No statistically significant correlations between the severity of allergic diseases and SLE disease activity were identified. Conclusions . The overall prevalence of allergic disease among pediatric patients with SLE is within the range of the general population. Severe and undiagnosed allergic diseases and SLE can coexist.