Successful Treatment of a Recalcitrant <i>Staphylococcus epidermidis</i> Prosthetic Knee Infection with Intraoperative Bacteriophage Therapy
Here, we present a case of a 79-year-old female with a recalcitrant <i>Staphylococcal epidermidis</i> prosthetic knee infection that was successfully treated with a single dose of adjuvant intra-articular bacteriophage therapy after debridement and implant retention surgery. The bacterio...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Here, we present a case of a 79-year-old female with a recalcitrant <i>Staphylococcal epidermidis</i> prosthetic knee infection that was successfully treated with a single dose of adjuvant intra-articular bacteriophage therapy after debridement and implant retention surgery. The bacteriophage used in this case, PM448, is the first ɛ<sup>2</sup> bacteriophage to be used in vivo. Currently the patient is without evidence of clinical recurrence and, interestingly, the patient had also suffered from debilitating aplastic anemia for over 2 years, which is recovering since receiving adjuvant bacteriophage therapy. |
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| Item Description: | 10.3390/ph14030231 1424-8247 |