In Silico and In Vitro Investigation of Cytotoxicity and Apoptosis of Acridine/Sulfonamide Hybrids Targeting Topoisomerases I and II
Background: Sulfonamide acridine derivatives have garnered significant attention from medicinal chemists due to their diverse range of biological activities. Methods: In this study, eleven compounds were synthesized according to the literature, and their impact on cell growth inhibition, induction o...
Saved in:
Main Authors: | Mohamed Badr (Author), Elshaymaa I. Elmongy (Author), Doaa Elkhateeb (Author), Yasmine S. Moemen (Author), Ashraf Khalil (Author), Hadeer Ali (Author), Reem Binsuwaidan (Author), Feby Awadallah (Author), Ibrahim El Tantawy El Sayed (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2024-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Antimicrobial Evaluation of Sulfonamides after Coupling with Thienopyrimidine Coplanar Structure
by: Elshaymaa I. Elmongy, et al.
Published: (2024) -
Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action
by: Marco Bragagni, et al.
Published: (2017) -
Synthesis, Biocidal and Antibiofilm Activities of New Isatin-Quinoline Conjugates against Multidrug-Resistant Bacterial Pathogens along with Their In Silico Screening
by: Elshaymaa I. Elmongy, et al.
Published: (2022) -
Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine-Thiosemicarbazone Derivatives
by: Gleyton Sousa, et al.
Published: (2022) -
Acridine Orange/exosomes increase the delivery and the effectiveness of Acridine Orange in human melanoma cells: A new prototype for theranostics of tumors
by: Elisabetta Iessi, et al.
Published: (2017)