Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis

Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnan...

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Bibliographic Details
Main Authors: Ahmed Arafa (Author), Xiaowen Wang (Author), Jia-Yi Dong (Author), Ehab S Eshak (Author)
Format: Book
Published: Taylor & Francis Group, 2021-07-01T00:00:00Z.
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Summary:Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies. Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I2 = 0.00%). Conclusion: MS is not associated with PE.
Item Description:1064-1955
1525-6065
10.1080/10641955.2021.1921792