Progress of Ginsenoside Rb1 in neurological disorders

Ginseng is frequently used in traditional Chinese medicine to treat neurological disorders. The primary active component of ginseng is ginsenoside, which has been classified into more than 110 types based on their chemical structures. Ginsenoside Rb1 (GsRb1)-a protopanaxadiol saponin and a typical g...

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Main Authors: Gongxia Ling (Author), Min Zhang (Author), Chizhang Chen (Author), Yan Wang (Author), Qiqi Gao (Author), Jianshun Li (Author), Hao Yuan (Author), Wenwen Jin (Author), Wei Lin (Author), Lingrong Yang (Author)
Format: Book
Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
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100 1 0 |a Gongxia Ling  |e author 
700 1 0 |a Min Zhang  |e author 
700 1 0 |a Chizhang Chen  |e author 
700 1 0 |a Yan Wang  |e author 
700 1 0 |a Qiqi Gao  |e author 
700 1 0 |a Jianshun Li  |e author 
700 1 0 |a Hao Yuan  |e author 
700 1 0 |a Wenwen Jin  |e author 
700 1 0 |a Wei Lin  |e author 
700 1 0 |a Lingrong Yang  |e author 
245 0 0 |a Progress of Ginsenoside Rb1 in neurological disorders 
260 |b Frontiers Media S.A.,   |c 2024-01-01T00:00:00Z. 
500 |a 1663-9812 
500 |a 10.3389/fphar.2024.1280792 
520 |a Ginseng is frequently used in traditional Chinese medicine to treat neurological disorders. The primary active component of ginseng is ginsenoside, which has been classified into more than 110 types based on their chemical structures. Ginsenoside Rb1 (GsRb1)-a protopanaxadiol saponin and a typical ginseng component-exhibits anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-autophagy properties in the nervous system. Neurological disorders remain a leading cause of death and disability globally. GsRb1 effectively treats neurological disorders. To contribute novel insights to the understanding and treatment of neurological disorders, we present a comprehensive review of the pharmacokinetics, actions, mechanisms, and research development of GsRb1 in neurological disorders. 
546 |a EN 
690 |a Ginsenoside Rb1 
690 |a pharmacokinetics 
690 |a actions 
690 |a mechanisms 
690 |a neurological disorders 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pharmacology, Vol 15 (2024) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fphar.2024.1280792/full 
787 0 |n https://doaj.org/toc/1663-9812 
856 4 1 |u https://doaj.org/article/7e2ee14a8a8e419da19c4957b976b80d  |z Connect to this object online.