Yizhiqingxin Formula Alleviates Cognitive Deficits and Enhances Autophagy via mTOR Signaling Pathway Modulation in Early Onset Alzheimer's Disease Mice

• Главные авторы: Yang Yang (Автор), Zhiyong Wang (Автор), Yu Cao (Автор), Jiangang Liu (Автор), Peng Li (Автор), Hao Li (Автор), Meixia Liu (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Предметы: article
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Alzheimer's disease (AD) is the most common type of dementia worldwide. The deposition of amyloid β (Aβ) is one of the most important pathological changes in AD. Autophagy, which mediates degradation of toxic proteins and maintains normal neuronal function, is dysfunctional in AD; dysfunctional...