Cell Internalization in Fluidic Culture Conditions Is Improved When Microparticles Are Specifically Targeted to the Human Epidermal Growth Factor Receptor 2 (HER2)

• প্রধান লেখক: Inmaculada Mora-Espí (Author), Elena Ibáñez (Author), Jorge Soriano (Author), Carme Nogués (Author), Thorarinn Gudjonsson (Author), Leonardo Barrios (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2019-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Purpose: To determine if the specific targeting of microparticles improves their internalization by cells under fluidic conditions. Methods: Two isogenic breast epithelial cell lines, one overexpressing the Human Epidermal Growth Factor Receptor 2 (HER2) oncogene (D492HER2) and highly tumorigenic an...