Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma

• Huvudupphovsmän: Eman R. Mohammed (Författare, medförfattare), Ghada F. Elmasry (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Inhibiting Cyclin-dependent kinase 2 (CDK2) has been established as a therapeutic strategy for the treatment of many cancers. Accordingly, this study aimed at developing a new set of quinazolinone-based derivatives as CDK2 inhibitors. The new compounds were evaluated for their anticancer activity ag...