Administration of intestinal mesenchymal stromal cells reduces colitis-associated cancer in C57BL/6J mice modulating the immune response and gut dysbiosis

• Main Authors: Laura Hidalgo-García (Author), Antonio Jesús Ruiz-Malagon (Author), Francisco Huertas (Author), María Jesús Rodríguez-Sojo (Author), José Alberto Molina-Tijeras (Author), Patricia Diez-Echave (Author), Patricia Becerra (Author), Benito Mirón (Author), Rocío Morón (Author), Alba Rodríguez-Nogales (Author), Julio Gálvez (Author), María Elena Rodríguez-Cabezas (Author), Per Anderson (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Patients with inflammatory bowel disease (IBD) have a higher risk of developing colitis-associated colorectal cancer (CAC) with poor prognosis. IBD etiology remains undefined but involves environmental factors, genetic predisposition, microbiota imbalance (dysbiosis) and mucosal immune d...