Identification of functional lipid metabolism biomarkers of brown adipose tissue aging

• Main Authors: Sabrina Gohlke (Author), Vyacheslav Zagoriy (Author), Alvaro Cuadros Inostroza (Author), Michaël Méret (Author), Carola Mancini (Author), Lukasz Japtok (Author), Fabian Schumacher (Author), Doreen Kuhlow (Author), Antonia Graja (Author), Heike Stephanowitz (Author), Markus Jähnert (Author), Eberhard Krause (Author), Andreas Wernitz (Author), Klaus-Jürgen Petzke (Author), Annette Schürmann (Author), Burkhard Kleuser (Author), Tim J. Schulz (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Aging is accompanied by loss of brown adipocytes and a decline in their thermogenic potential, which may exacerbate the development of adiposity and other metabolic disorders. Presently, only limited evidence exists describing the molecular alterations leading to impaired brown adipogenes...