Inhibitory Effects of Rhaponticin on Osteoclast Formation and Resorption by Targeting RANKL-Induced NFATc1 and ROS Activity

• Үндсэн зохиолчид: Jianbo He (Зохиогч), Kai Chen (Зохиогч), Tiancheng Deng (Зохиогч), Jiewei Xie (Зохиогч), Kunjing Zhong (Зохиогч), Jinbo Yuan (Зохиогч), Ziyi Wang (Зохиогч), Zhifeng Xiao (Зохиогч), Ronghe Gu (Зохиогч), Delong Chen (Зохиогч), Xiaojuan Li (Зохиогч), Dingkun Lin (Зохиогч), Jiake Xu (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The extravagant osteoclast formation and resorption is the main cause of osteoporosis. Inhibiting the hyperactive osteoclastic resorption is considered as an efficient treatment for osteoporosis. Rhaponticin (RH) is a small molecule that has been reported to possess anti-inflammatory, anti-allergic,...