AGO-accessible anticancer siRNAs designed with synergistic miRNA-like activity
Small interfering RNAs (siRNAs) therapeutically induce RNA interference (RNAi) of disease-causing genes, but they also silence hundreds of seed-matched off-targets as behaving similar to microRNAs (miRNAs). miRNAs control the pathophysiology of tumors, wherein their accessible binding sites can be s...
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Main Authors: | Dowoon Gu (Author), Seung Hyun Ahn (Author), Sangkyeong Eom (Author), Hye-Sook Lee (Author), Juyoung Ham (Author), Dong Ha Lee (Author), You Kyung Cho (Author), Yongjun Koh (Author), Elizaveta Ignatova (Author), Eun-Sook Jang (Author), Sung Wook Chi (Author) |
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Format: | Book |
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Elsevier,
2021-03-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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