Tyrosine Phosphorylation of Botulinum Neurotoxin Protease Domains
Botulinum neurotoxins are most potent of all toxins. Their N-terminal light chain domain (Lc) translocates into peripheral cholinergic neurons to exert its endoproteolytic action leading to muscle paralysis. Therapeutic development against these toxins is a major challenge due to their in vitro and...
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Main Authors: | Stephen eToth (Author), Ernst E Brueggemann (Author), George A Oyler (Author), Leonard A Smith (Author), Harry B. Hines (Author), S. Ashraf eAhmed (Author) |
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Format: | Book |
Published: |
Frontiers Media S.A.,
2012-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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