Cardiac Dysfunction Associated with Lacosamide in a Premature Infant with Hypoxic Ischemic Encephalopathy: A Case Report

Lacosamide (Vimpat Harris FRC Corporation, 2022 UCB, Inc. Smyrna, GA 30080) is an antiseizure medication, which acts through blockage of voltage-gated neuronal sodium channels. Its recent implementation in the neonatal population has been extrapolated from adult and pediatric data suggesting a favor...

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Bibliographic Details
Main Authors: Trassanee Chatmethakul (Author), Amy H. Stanford (Author), Danielle R. Rios (Author), Adrianne R. Bischoff (Author), Theresa Czech (Author), Patrick J. McNamara (Author)
Format: Book
Published: Thieme Medical Publishers, Inc., 2024-07-01T00:00:00Z.
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Summary:Lacosamide (Vimpat Harris FRC Corporation, 2022 UCB, Inc. Smyrna, GA 30080) is an antiseizure medication, which acts through blockage of voltage-gated neuronal sodium channels. Its recent implementation in the neonatal population has been extrapolated from adult and pediatric data suggesting a favorable safety profile. Of note, preterm infants have unique developmental characteristics that may predispose them to increased risk of adverse reactions. We present a case of a preterm neonate who developed left ventricular dysfunction coinciding with the initiation of lacosamide.
Item Description:2157-6998
2157-7005
10.1055/a-2447-8662