Cover Image

Retinal Delivery of the Protein Kinase C-β Inhibitor Ruboxistaurin Using Non-Invasive Nanoparticles of Polyamidoamine Dendrimers

Ruboxistaurin (RBX) is an anti-vascular endothelial growth factor (anti-VEGF) agent that is used in the treatment of diabetic retinopathy and is mainly given intravitreally. To provide a safe and effective method for RBX administration, this study was designed to develop RBX nanoparticles using poly...

Full description

Saved in:

Bibliographic Details
Main Authors:	Rehab A. Alshammari (Author), Fadilah S. Aleanizy (Author), Amal Aldarwesh (Author), Fulwah Y. Alqahtani (Author), Wael A. Mahdi (Author), Bushra Alquadeib (Author), Qamraa H. Alqahtani (Author), Nazrul Haq (Author), Faiyaz Shakeel (Author), Hosam G. Abdelhady (Author), Ibrahim A. Alsarra (Author)
Format:	Book
Published:	MDPI AG, 2022-07-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Determination of Ruboxistaurin analysis in rat plasma utilizing LC-MS/MS technique
by: Bushra T. AlQuadeib, et al.
Published: (2023)

Preparation, characterization, and antibacterial activity of diclofenac-loaded chitosan nanoparticles
by: Fulwah Yahya Alqahtani, et al.
Published: (2019)

MicroRNA-539-5p-Loaded PLGA Nanoparticles Grafted with iRGD as a Targeting Treatment for Choroidal Neovascularization
by: Jouri S. Alanazi, et al.
Published: (2022)

Binding interaction between daptomycin and polyamidoamine dendrimer
by: Boontarika Chanvorachote
Published: (2014)

Anti-quorum sensing activity of poly-amidoamine dendrimer generation 5 dendrimer loaded kinase inhibitor peptide against methicillin-resistant Staphylococcus aureus
by: Naifa A. Alenazi, et al.
Published: (2024)

An Alternative Approach for Acetylation of Amine Terminated Polyamidoamine (PAMAM) Dendrimer
by: Surya Prakash Gautam, et al.
Published: (2015)

Measurement and evaluation of the effects of pH gradients on the antimicrobial and antivirulence activities of chitosan nanoparticles in Pseudomonas aeruginosa
by: Fadilah Sfouq Aleanizy, et al.
Published: (2018)

Evaluation of cationic polyamidoamine dendrimers’ dermal toxicity in the rat skin model
by: Winnicka K, et al.
Published: (2015)

Potential Use of Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for siRNA
by: Taishi Higashi, et al.
Published: (2011)

A Mixed-Surface Polyamidoamine Dendrimer for In Vitro and In Vivo Delivery of Large Plasmids
by: Bhairavi Srinageshwar, et al.
Published: (2020)

Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa
by: Hamed Sheykhloo, et al.
Published: (2021)

Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for DNA, shRNA and siRNA
by: Hidetoshi Arima, et al.
Published: (2012)

Conjugation of Short Oligopeptides to a Second-Generation Polyamidoamine Dendrimer Shows Antibacterial Activity
by: Namyoung Kang, et al.
Published: (2023)

Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer
by: Gao S, et al.
Published: (2015)

Chitosan loaded RNA polymerase inhibitor nanoparticles increased attenuation in toxin release from Streptococcus pneumonia
by: Fulwah Yahya Alqahtani, et al.
Published: (2023)

An evaluation of E. coli in urinary tract infection in emergency department at KAMC in Riyadh, Saudi Arabia: retrospective study
by: Menyfah Q. Alanazi, et al.
Published: (2018)

Photocytotoxicity studies of polyamidoamine (PAMAM) dendrimer and its glucoheptoamidated derivative as delivery drug systems in local PUVA photochemotherapy
by: Katarzyna Borowska, et al.
Published: (2017)

Future-Oriented Nanosystems Composed of Polyamidoamine Dendrimer and Biodegradable Polymers as an Anticancer Drug Carrier for Potential Targeted Treatment
by: Katarzyna Strzelecka, et al.
Published: (2024)

Preparation and characterization of Meta-bromo-thiolactone calcium alginate nanoparticles
by: Esra Kamal Eltayb, et al.
Published: (2022)

Status of infectious disease content in the professional pharmacy curriculum in Saudi Arabia: Results of a national survey
by: Fulwah Y. Alqahtani, et al.
Published: (2021)

Saudi Arabia stands as one of the leading countries for COVID-19 containment
by: Fadilah Sfouq Aleanizy, et al.
Published: (2020)

Evaluation of the Clinical Outcome and Cost Analysis of Antibiotics in the Treatment of Acute Respiratory Tract Infections in the Emergency Department in Saudi Arabia
by: Menyfah Q. Alanazi, et al.
Published: (2022)

Galactosylated hydroxyl‐polyamidoamine dendrimer targets hepatocytes and improves therapeutic outcomes in a severe model of acetaminophen poisoning‐induced liver failure
by: Joshua E. Porterfield, et al.
Published: (2023)

Formulation and evaluation of docetaxel nanosuspensions: In-vitro evaluation and cytotoxicity
by: Mohamed A. Ibrahim, et al.
Published: (2019)

Isotretinoin self-nano-emulsifying drug delivery system: Preparation, optimization and antibacterial evaluation
by: Rihaf Alfaraj, et al.
Published: (2024)

Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs
by: Elisabet Martí Coma-Cros, et al.
Published: (2018)

Improved delivery of miR-1296 loaded cationic nanoliposomes for effective suppression of triple negative breast cancer
by: Lamyaa Albakr, et al.
Published: (2021)

Polyamidoamine-stabilized and hyaluronic acid-functionalized gold nanoparticles for cancer therapy
by: Marwan Abdelmahmoud Abdelkarim Maki, et al.
Published: (2023)

Dendrimers as Antiamyloid Agents
by: Svetlana A. Sorokina, et al.
Published: (2022)

Dendrimers Fundamentals and Applications
Published: (2018)

Clinical characteristics and risk factors of patients with severe COVID-19 in Riyadh, Saudi Arabia: A retrospective study
by: Fadilah S. Aleanizy, et al.
Published: (2021)

Assessment of Knowledge, Attitude, and Practice of Security and Safety Workers Toward the COVID-19 Pandemic: A Cross-Sectional Study
by: Maha M. AlRasheed, et al.
Published: (2021)

Development and validation of a new HPLC analytical method for the determination of diclofenac in tablets
by: Bushra Tuwfeeq Alquadeib
Published: (2019)

Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues
by: Kanika Madaan, et al.
Published: (2014)

Outcomes associated with tocilizumab with or without corticosteroid versus dexamethasone for treatment of patients with severe to critical COVID-19 pneumonia
by: Hajar AlQahtani, et al.
Published: (2022)

Evaluation of the bioavailability of hydrocortisone when prepared as solid dispersion
by: Mohammad A. Altamimi, et al.
Published: (2019)

Radical Dendrimers Based on Biocompatible Oligoethylene Glycol Dendrimers as Contrast Agents for MRI
by: Songbai Zhang, et al.
Published: (2020)

Dendrimers and Derivatives as Multifunctional Nanotherapeutics for Alzheimer's Disease
by: Débora A. Moreira, et al.
Published: (2023)

Dendrimer-Mediated Delivery of DNA and RNA Vaccines
by: Lyubov A. Kisakova, et al.
Published: (2023)

Dendrimers for siRNA Delivery
by: Swati Biswas, et al.
Published: (2013)