Circulating Heat Shock Proteins in Women With a History of Recurrent Vulvovaginitis

Objective: Predisposing factors influencing recurrences of bacterial vaginosis (BV) or vaginitis from Candida remain unidentified for most women. As a component of studies to determine host susceptibility factors to genital tractiiafeetions in women, we measured expression of the 60-kDa and 70-kDa h...

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Main Authors: P. C. Giraldo (Author), A. D. Ribeiro-Filho (Author), J. A. Simões (Author), A. Neuer (Author), S. B. N. Feitosa (Author), S. S. Witkin (Author)
Format: Book
Published: Hindawi Limited, 1999-01-01T00:00:00Z.
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Summary:Objective: Predisposing factors influencing recurrences of bacterial vaginosis (BV) or vaginitis from Candida remain unidentified for most women. As a component of studies to determine host susceptibility factors to genital tractiiafeetions in women, we measured expression of the 60-kDa and 70-kDa heat shock proteins (hsp60 and hsp70, respectively) in the circulation of women with or without a history of recurrent BV or candidal vaginitis and with or without a current lower genital tract infection. Heat shock protein expression is associated with a down-regulation of proinflammatory immune responses that would inhibit microbial infection.
Item Description:1064-7449
1098-0997
10.1155/S1064744999000204