Prediction of the anti-inflammatory mechanisms of curcumin by module-based protein interaction network analysis

• Main Authors: Yanxiong Gan (Author), Shichao Zheng (Author), Jan P.A. Baak (Author), Silei Zhao (Author), Yongfeng Zheng (Author), Nini Luo (Author), Wan Liao (Author), Chaomei Fu (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Curcumin, the medically active component from Curcuma longa (Turmeric), is widely used to treat inflammatory diseases. Protein interaction network (PIN) analysis was used to predict its mechanisms of molecular action. Targets of curcumin were obtained based on ChEMBL and STITCH databases. Protein-pr...