UGT1A1 mutation association with increased bilirubin levels and severity of unconjugated hyperbilirubinemia in ABO incompatible newborns of China

• Main Authors: Hui Yang (Author), Fen Lin (Author), Zi-kai Chen (Author), Lin Zhang (Author), Jia-Xin Xu (Author), Yong-Hao Wu (Author), Jing-Ying Gu (Author), Yu-Bin Ma (Author), Jian-Dong Li (Author), Li-Ye Yang (Author)
• Formato: Livro
• Publicado em: BMC, 2021-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Neonatal hyperbilirubinemia causing jaundice is common in East Asian population. Uridine diphosphate glucuronosyltransferase isoenzyme (UGT1A1) glucuronidates bilirubin and converts the toxic form of bilirubin to its nontoxic form. Method A retrospective study was conducted to re...