Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/- mice corpus cavernosum microcirculation

• Main Authors: Miguel A. Olivencia (Author), Erika Esposito (Author), Vincenzo Brancaleone (Author), Sigismondo Castaldo (Author), Giuseppe Cirino (Author), Francisco Pérez-Vizcaino (Author), Raffaella Sorrentino (Author), Roberta d'Emmanuele di Villa Bianca (Author), Emma Mitidieri (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The corpus cavernosum (CC) is a highly vascularized tissue and represents an excellent example of microcirculation. Indeed, erectile dysfunction is considered an early index of cardiovascular disease. Hydrogen sulfide (H2S) at the vascular level is endogenously produced from L-cysteine mainly by the...