sIgA, peroxidase and collagenase in saliva of smokers aggressive periodontal patients

Background: Tobacco smoking is strongly associated with destructive periodontal disease, alveolar bone loss and poor response to periodontal therapy. The aim of this study was to investigate the effect of smoking on antimicrobials and destructive proteins in the saliva of patients with generalized a...

Full description

Saved in:
Bibliographic Details
Main Authors: Myriam A. Koss (Author), Cecilia E. Castro (Author), Agustina M. Gramajo (Author), María E. López (Author)
Format: Book
Published: Elsevier, 2016-11-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_814e08a8416f4e3ea7abf37969df26e2
042 |a dc 
100 1 0 |a Myriam A. Koss  |e author 
700 1 0 |a Cecilia E. Castro  |e author 
700 1 0 |a Agustina M. Gramajo  |e author 
700 1 0 |a María E. López  |e author 
245 0 0 |a sIgA, peroxidase and collagenase in saliva of smokers aggressive periodontal patients 
260 |b Elsevier,   |c 2016-11-01T00:00:00Z. 
500 |a 2212-4268 
500 |a 10.1016/j.jobcr.2016.05.003 
520 |a Background: Tobacco smoking is strongly associated with destructive periodontal disease, alveolar bone loss and poor response to periodontal therapy. The aim of this study was to investigate the effect of smoking on antimicrobials and destructive proteins in the saliva of patients with generalized aggressive periodontal disease. Material and methods: The study group consisted of 55 adult subjects. They were classified according to their clinical diagnoses either as having generalized aggressive periodontitis (n = 27; 13 smokers and 14 non-smokers) or as periodontitis-free control group (n = 28; 14 smokers and 14 non-smokers). Total proteins, sIgA, peroxidase and collagenase were quantified in whole saliva. Data were analyzed using one-way ANOVA and Tukey tests. Results: Statistical differences were found between smokers with periodontal disease and healthy control subjects for sIgA, and between non-smokers with periodontal disease and healthy control subjects for peroxidase. Collagenase activity was higher in smokers and non-smokers with periodontal disease, and tobacco use was found to increase collagenase activity in healthy subjects. Conclusion: Whole saliva from all patients with periodontal disease had higher sIgA and lower peroxidase content. Smokers with periodontitis had higher sIgA than smokers without periodontitis. Smokers with and without periodontitis had higher collagenase activity than non-smokers (with and without periodontitis). 
546 |a EN 
690 |a Saliva 
690 |a Smokers 
690 |a Aggressive periodontitis 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Journal of Oral Biology and Craniofacial Research, Vol 6, Iss , Pp S24-S28 (2016) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2212426816300318 
787 0 |n https://doaj.org/toc/2212-4268 
856 4 1 |u https://doaj.org/article/814e08a8416f4e3ea7abf37969df26e2  |z Connect to this object online.