Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes

• Main Authors: Rebecca Piccarducci (Author), Simona Daniele (Author), Jonathan Fusi (Author), Lucia Chico (Author), Filippo Baldacci (Author), Gabriele Siciliano (Author), Ubaldo Bonuccelli (Author), Ferdinando Franzoni (Author), Claudia Martini (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The allele epsilon 4 (ε4) of apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer's disease (AD). ApoE protein plays a pivotal role in the synthesis and metabolism of amyloid beta (Aβ), the major component of the extracellular plaques that constitute AD pathological hallma...